Everything about ceesdekker
Everything about ceesdekker
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Midway by way of his career, Cees Dekker reinvented himself. Soon after years of hardcore physics, he shifted his emphasis to ‘nanobiology’ at the switch on the millennium. A time period he coined himself, like a make any difference of truth.
Our group experiments bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells which will autonomously divide. Our major curiosity lies in mobile division, chromatin framework, and spatial Handle.
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
Our get the job done was speedily adopted up by Other people, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 printed their findings on transistors created from one- and multi-walled carbon nanotubes in Used Physics Letters.
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Our investigate ranges within the biophysics of DNA to artificial cells and outside of. You should take a look underneath with the spectrum of our latest initiatives.
All parameters have been the exact same for every panel in this video, except for the Preliminary placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early as a consequence of translocation of the rod through the pore are marked by a grey background.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
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Pretty great, but that wasn’t seriously where my curiosity lay. I needed to pioneer and I had the feeling which was no longer attainable, as the most fascinating basic insights experienced already been uncovered. But my field had developed numerous fascinating new equipment to measure personal molecules. I decided that I desired to use this to biology, to look at it from a physical standpoint.’
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2004, discovery of new physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and 1st cees dekker solitary-molecule study of DNA translocation by a restriction-modification enzyme.